المؤلف | Dhiaedeen A. Rahim Hussein , Alaa A. Rasool Hassan , Hussein H.Mohamad , Myada S. SadeqMajd S. Hamoudi | |
تاريخ الانضمام | 2024-10-17T07:54:57Z | |
تاريخ الإتاحة | 2024-10-17T07:54:57Z | |
تاريخ النشر | 2019 | |
معرّف المصادر الموحد | http://www.iiir-mim.gov.iq/xmlui/handle/123456789/1766 | |
الملخص | Meloxicam is a non steroidal anti-inflammatory drug (NSAIDs) used for treatment of acute exacerbation of inflammatory rheumatoid. Meloxicam injection is a sterile aqueous solution contains Meloxicam 10mg/1ml with other additional ingredients sodium chloride for isotonicity and glycin-sodium hydroxide as buffering agent. Different formulations were prepared in order to asses the influence of light , atmospheric oxygen and antioxidant that sure stability, safety , effectiveness and improve the physical appearance and prolong the shelf life of formulation , the best one was selected and the selection performed according to physical criteria that are comply with the specification of the united state pharmacopeia (USP) . The stability study was carried out after exposure the formula to different temperatures and humidity especially ( 25 °C /60% RH,30 °C /65% RH and 40 °C /75% RH ) in order to reach a suitable formula which meets the requirements of pharmacopeial specifications .
The results of stability study was indicated that the studied formula was stable and no physico- chemical changes were observed. | ar |
اللغة | en | ar |
الناشر | Corporation for Research and Industrial Development, Ibn Sina Center for Researches | ar |
موضوع | Meloxicam, injection, non-steroidal, inflammatory | ar |
العنوان | Meloxicam )10 mg /1ml w/v) for Intramuscular (I.M) Injection Only تصييغ تركيبة ميلوكسيكام (10 mg /1ml) للحقن العضلي فقط | ar |
النوع | Article | ar |