Iraqi Pharmaceutical Formula for Dried Aluminum Hydroxide 225mg/5ml , Magnesium Hydroxide 200mg/5ml and Simethicone 25mg/5ml Oral Suspension to Treat Dyspepsia, Heartburn and Flatulence with it,s Stability Study . تركيبة صيدلانية عراقية لمستحضرهيدروكسيد الالمنيوم الجاف 225ملغم /5مل , هيدروكسيد المغنسيوم 200 ملغم /5 مل وسميثكون 25ملغم /5مل معلق فموي لعلاج عسر الهضم ، الحرقة، وانتفاخ البطن مع دراسة ثباتيتها.

Abstract

This work has been carried out to develop national drug product contains dried aluminum hydroxide (225 mg) , magnesium hydroxide (200 mg) and simethicon (25mg / 5ml) as oral suspension is used to treat dyspepsia, heartburn, flatulence .Several formulations were prepared using different suspensions bases , preservatives and suspending agent. Selection of best formula relied solely on physico-chemical testing . Stability study was conducted on the product for (6) months at different temperatures to determine the expiration date and the best storage conditions. From the study we obtained an antiviral suspension of good homogeneity. The expiry date calculated to be not less than (3) years.