Iraqi Pharmaceutical Formula For Diclofenac Diethylamine Emulgel (1.16%w/w) for the Treatment of Inflammation aتركيبة صيدلانية عراقية لمستحضر ايملجل دايكلوفيناك داي اثيل امين(1.16%) وزن/ وزن لعلاج التهاب وآلام المفاصل والعضلات مع دراسة ثباتيتها nd Pain of Joints and Muscles with its Stability Study

Abstract

This work has been carried out to develop national drug product contains (1.16 %) diclofenac diethylamineas an emulgel, it is used for the local symptomatic relief of pain and inflammation in trauma of the tendons, ligaments , muscles and joints e.g. due to sprains , strains and bruises,localized forms of soft tissue rheumatism. Several emulgel formulations were prepared using different emulgels bases, preservatives and humectants. Selection of best formula relied solely on physicochemical testing of sample exposed to thermal stresses. Stability study was conducted on the product for (6) months at different temperatures and relative humidity to determine the expiration date and the best storage conditions. We obtained non-steroidal anti-inflammatory (NSAID) emulgel of good homogeneity, softness and adhesivity.The expiry date calculated to be not less than (3) years.