تركيبة صيدلانية عراقية لمستحضر ميترونيدازول جل مهبلي 75 . 0 % وزن/ وزن مضاد للفطريات مع دراسة ثباتيتها Iraqi Pharmaceutical Formula for Metronidazole Vaginal Gel 0.75 % w/w Anti Fungal with It,s Stability Study

Abstract

This work is concerned with elicitation of new Iraqi pharmaceutical formula for metronidazole vaginal gel 0.75 % with its stability study . This drug is used for treatment of certain types of bacterial infections in the vagina . This formula has an economical importance in presenting safe, cheap and efficient drug for the patient . Different batches have prepared including different gel bases , preservative and humectants . Selection for better combination relied solely on physical testing of sample exposed to thermal stresses. The formula was studied for six months at different temperatures to determine the expirydate. From theis study we obtained vaginal gel of good homogeneity, softness and adhesivity . The expiration date calculated to be not less than (2) years.