Formulation of Probiotics capsule as an oral Dietary Supplement./تركيبة البروبايوتيك كبسول كمكمل غذائي فموي

Abstract

Probiotic capsule is a simple formula that contains a friendly microbes strains Lactobacillus acidophilus. The aim of study is to develop anew pharmaceutical formula containes one billion live cells of bacteria ( Lactobacillus acidophilus).which has the ability to survive in the intestinal tract used as dietary supplement. In this present study, high quality probiotics were used, vegetarian empty capsules are gelatin free, offer stable performance and are the most recommended shells in the pharmaceutical industry today. Several trials were carried out to prepare stable formula consisting of a mixture of freeze dried Lactobacillus acidophilus bacteria, free from artificial colors, flavors, preservatives, yeast and gluten. Evaluation of final formula was carried out to identify live active cells of survived bacteria founds in the formula, microbial limit test and the activity against pathogenic bacteria. The stability study was carried out for three and six months after storing at room temperature below ( 30°C). Now a days Probiotic capsules are widely used as dietary supplement used to help building and maintaining a healthy digestive system ,so the present project may be used as a promised formula in this field.