Formulation of Ibuprofen 600 mg Effervescent Powder as Oral Dosage Form/تصييغ الابيوبروفين 600ملغم باودر فوار كجرعة دوائية فموية

Abstract

Ibuprofen is one of the most widely used drug to relieve mild to moderate pain such as dental discomfort ,post-operative pain ,headaches, menstruation pain as well as treatment for fever rheumatoid arthritis , osteoarthritis and to treat soft tissue injuries such as sprains , tendonitis among other condition. It belong to the group of drug called non-steroidal anti inflammatory drug (NSAID). The aim of this research is to formulate of Ibuprofen(600mg) effervescent powder (sachet) which is abig wide spread uses in Iraqi drug Two formula were prepared using different additives , after has been checked and ensure getting the required physical and chemical specification including the assay of the active ingredient exposed the selected batches to different temperatures by monitoring and assessing the change taken place , The selected formula was introduced in to exaggerated different temperatures ,the shelf-life was calculated.